The implications of immunopathology for parasite evolution.

@article{Best2012TheIO,
  title={The implications of immunopathology for parasite evolution.},
  author={Alex Best and Gr{\'a}inne H. Long and Andy White and Mike Boots},
  journal={Proceedings. Biological sciences},
  year={2012},
  volume={279 1741},
  pages={3234-40}
}
By definition, parasites harm their hosts, but in many infections much of the pathology is driven by the host immune response rather than through direct damage inflicted by parasites. While these immunopathological effects are often well studied and understood mechanistically in individual disease interactions, there remains relatively little understanding of their broader impact on the evolution of parasites and their hosts. Here, we theoretically investigate the implications of… CONTINUE READING