The impact of the absence of glycopeptidolipids on the ultrastructure, cell surface and cell wall properties, and phagocytosis of Mycobacterium smegmatis.

@article{Etienne2002TheIO,
  title={The impact of the absence of glycopeptidolipids on the ultrastructure, cell surface and cell wall properties, and phagocytosis of Mycobacterium smegmatis.},
  author={Gilles Etienne and Christelle Villeneuve and Helen Billman-Jacobe and Catherine Astarie-Dequeker and Marie-Ange Dupont and Mamadou Daff{\'e}},
  journal={Microbiology},
  year={2002},
  volume={148 Pt 10},
  pages={3089-100}
}
Glycopeptidolipids (GPLs) are a class of species- or type-specific mycobacterial lipids and major constituents of the cell envelopes of many non-tuberculous mycobacteria. To determine the function of GPLs in the physiology of these bacteria, a mutant of Mycobacterium smegmatis in which the gene encoding a mycobacterial nonribosomal peptide synthetase has been inactivated by transposon mutagenesis was analysed. Labelling experiments indicated that half of the bacterial GPLs were located on the… CONTINUE READING
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