The impact of surgical intervention and antibiotics on MRONJ stage II and III - Retrospective study.

@article{Zirk2017TheIO,
  title={The impact of surgical intervention and antibiotics on MRONJ stage II and III - Retrospective study.},
  author={Matthias L Zirk and Matthias Kreppel and Johannes Buller and Julij Pristup and Franziska S Peters and Timo Dreiseidler and Max Zinser and Joachim E. Z{\"o}ller},
  journal={Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery},
  year={2017},
  volume={45 8},
  pages={1183-1189}
}
OBJECTIVES Metastatic bone disease and osteoporosis are the main indications for bisphosphonates and anti-resorptive agent therapy. Inhibition of bone turnover and angiogenesis are mainly responsible for the development of Medication Related Osteonecrosis of Jaws (MRONJ) as therapeutic side-effect. Yet, the role of infection for the development and… CONTINUE READING