The impact of supplemental macular carotenoids in Alzheimer's disease: a randomized clinical trial.

@article{Nolan2015TheIO,
  title={The impact of supplemental macular carotenoids in Alzheimer's disease: a randomized clinical trial.},
  author={J. Nolan and E. Loskutova and A. Howard and R. Mulcahy and R. Moran and J. Stack and M. Bolger and R. Coen and Jessica L Dennison and K. O. Akuffo and Niamh Owens and R. Power and D. Thurnham and S. Beatty},
  journal={Journal of Alzheimer's disease : JAD},
  year={2015},
  volume={44 4},
  pages={
          1157-69
        }
}
BACKGROUND Patients with Alzheimer's disease (AD) exhibit significantly less macular pigment (MP) and poorer vision when compared to control subjects. OBJECTIVE To investigate supplementation with the macular carotenoids on MP, vision, and cognitive function in patients with AD versus controls. METHODS A randomized, double-blind clinical trial with placebo and active arms. 31 AD patients and 31 age-similar control subjects were supplemented for six months with either Macushield (10 mg meso… Expand
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