The impact of stressors on immune and central neurotransmitter activity: bidirectional communication.

@article{Anisman1993TheIO,
  title={The impact of stressors on immune and central neurotransmitter activity: bidirectional communication.},
  author={Hymie Anisman and Steven J. Zalcman and Robert M. Zacharko},
  journal={Reviews in the neurosciences},
  year={1993},
  volume={4 2},
  pages={
          147-80
        }
}
Antigenic challenge may have broad ranging effects which include not only immunological changes, but also endocrine and central neurotransmitter repercussions, and may thus elicit profound behavioral sequelae. Commensurate with the notion that bidirectional communication exists between the immune and central nervous systems it has been demonstrated that manipulations which influence central neurotransmitter or endocrine activity provoke alterations of immune functioning, and conversely… CONTINUE READING
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