The impact of several phenotypic features at diagnosis on survival of patients with myelodysplastic syndromes.

@article{ReisAlves2010TheIO,
  title={The impact of several phenotypic features at diagnosis on survival of patients with myelodysplastic syndromes.},
  author={Suiellen C. Reis-Alves and Fab{\'i}ola Traina and S T Saad and Konradin Metze and Irene Lorand-Metze},
  journal={Neoplasma},
  year={2010},
  volume={57 6},
  pages={
          530-6
        }
}
Multiparametric flow cytometry is a useful co-criterion for diagnostic confirmation of MDS in patients with peripheral cytopenias and a normal karyotype. We examined the impact on patients' survival of several phenotypic aberrancies detected by a small 4-color panel of monoclonal antibodies (MoAbs). Diagnosis of the patients (54) was made by WHO criteria using peripheral blood counts, bone marrow (BM) morphology and karyotype. Flow cytometry was performed at diagnosis, and features obtained… 
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Methods Citations
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Immunophenotyping in Myelodysplastic Syndromes Can Add Prognostic Information to Well-Established and New Clinical Scores
TLDR
Immunophenotypic analysis of myelomonocytic progenitors provides additional prognostic information to all clinical scores studied and IPSS-R improved risk stratification in MDS compared to the former scores.
Improving the differential diagnosis between myelodysplastic syndromes and reactive peripheral cytopenias by multiparametric flow cytometry: the role of B-cell precursors
TLDR
Analysis of myelomonocytic precursors and CD34+ cells was satisfactory for the differential diagnosis between reactive PB cytopenias and MDS, and the most specific alterations were found in CD34+, the most important aberrancies in MDS.
Utility of peripheral blood flow cytometry in differentiating low grade versus high grade myelodysplastic syndromes (MDS) and in the evaluation of cytopenias.
TLDR
The data suggests that FC of PB may be helpful in the work-up of patients with cytopenias and in the differential diagnosis of low-grade vs. high-grade MDS.
Bone marrow dendritic cells are reduced in patients with high-risk myelodysplastic syndromes.
Computerized texture analysis of atypical immature myeloid precursors in patients with myelodysplastic syndromes: an entity between blasts and promyelocytes
TLDR
BM atypical immature myeloid precursors are difficult to be correctly classified in routine cytology, and computerized texture analysis indicates a nuclear chromatin remodeling more close to the promyelocyte, thus indicating an asynchronous intermediate maturation stage between blast and promYelocyte.
Characteristics of the phenotypic abnormalities of bone marrow cells in childhood myelodysplastic syndromes and juvenile myelomonocytic leukemia
Immunophenotyping of bone marrow (BM) hemopoietic precursors is useful for diagnosis of adult myelodysplastic syndrome (MDS), but data concerning pediatric patients are limited. We analyzed…
Monocyte phenotypic aberrancies are an unfavorable prognostic factor in patients with myelodysplastic syndromes and low IPSS-R scores.

References

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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