The impact of radiosurgery fractionation and tumor radiobiology on the local control of brain metastases.

Abstract

OBJECT Experience with whole-brain radiation therapy for metastatic tumors in the brain has identified a subset of tumors that exhibit decreased local control with fractionated regimens and are thus termed radioresistant. With the advent of frameless radiosurgery, fractionated radiosurgery (2-5 fractions) is being used increasingly for metastatic tumors… (More)
DOI: 10.3171/2013.8.JNS122177

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