The impact of prolonged lower limb ischemia on amputation, mortality, and functional status: the FRIENDS registry.

@article{Duval2014TheIO,
  title={The impact of prolonged lower limb ischemia on amputation, mortality, and functional status: the FRIENDS registry.},
  author={Sue J Duval and Hong Hak Keo and Niki C. Oldenburg and Iris Baumgartner and Michael R. Jaff and James M. Peacock and Alexander S Tretinyak and Timothy D. Henry and Russell V. Luepker and Alan T. Hirsch},
  journal={American heart journal},
  year={2014},
  volume={168 4},
  pages={577-87}
}
BACKGROUND Peripheral artery disease (PAD) is a major cause of cardiovascular ischemic events and amputation. Knowledge gaps exist in defining and measuring key factors that predict these events. The objective of this study was to assess whether duration of limb ischemia would serve as a major predictor of limb and patient survival. METHODS The FReedom from Ischemic Events: New Dimensions for Survival (FRIENDS) registry enrolled consecutive patients with limb-threatening peripheral artery… CONTINUE READING