The impact of prenatal exposure to air pollution on childhood wheezing and asthma: A systematic review

@article{Hehua2017TheIO,
  title={The impact of prenatal exposure to air pollution on childhood wheezing and asthma: A systematic review},
  author={Zhang He-hua and Chang Qing and Gao Shanyan and Wu Qijun and Zhao Yuhong},
  journal={Environmental Research},
  year={2017},
  volume={159},
  pages={519–530}
}
Background and objectives: There has been no clear consensus about whether prenatal exposure to air pollution contributes to the development of wheezing and asthma in children. We conducted a systematic review to analyze the association between exposure to different pollutants during pregnancy and the development of childhood wheezing and asthma. Methods: We systematically reviewed epidemiological studies published through June 6, 2017 available in the MEDLINE and Web of Science databases. We… Expand
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The impact of prenatal exposure to PM2.5 on childhood asthma and wheezing: a meta-analysis of observational studies
TLDR
This meta-analysis indicated that the impact of PM2.5 on childhood asthma and wheezing begins as early as utero, so regulating pollutant emission standards and strengthening prenatal protection are crucial to maternal and child health. Expand
Long-term impacts of prenatal and infant exposure to fine particulate matter on wheezing and asthma
TLDR
Limited and inconsistent evidence is suggestive of an association between early life PM2.5 exposure and wheezing/asthma and large standardized studies are needed to explore the associations and identify vulnerable populations. Expand
Effect modification of perinatal exposure to air pollution and childhood asthma incidence
TLDR
Enhanced impacts were found among children born to mothers with asthma, who smoked during pregnancy or lived in urban areas during pregnancy, males and children born preterm or of low birthweight. Expand
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TLDR
The available findings support the hypothesis of the ‘fetal origins of childhood allergy,’ with new implications for the effective control and early prevention of childhood allergies. Expand
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TLDR
The link between air pollution and pediatric asthma morbidity is supported by the recent relevant literature and continued efforts are needed to identify the most vulnerable populations and develop strategies to reduce exposures and improve air quality. Expand
Spatiotemporal Variations in Ambient Ultrafine Particles and the Incidence of Childhood Asthma.
TLDR
Exposure to UFPs during a critical period of lung development was linked to the onset of asthma in children, independent of PM2.5 and NO2.2, and exposure during the second trimester of pregnancy remained positively associated with asthma incidence. Expand
Maternal exposure to PM2.5 during pregnancy and asthma risk in early childhood
TLDR
Later phases of prenatal lung development may be particularly sensitive to the developmental toxicity of PM2.5, and associations between prenatal fine particulate matter exposure and asthma at age 4 are assessed. Expand
Prenatal use of cleaning and scented products and its association with childhood asthma, asthma symptoms, and mental health and developmental comorbidities
TLDR
Preliminary results indicate prenatal exposure to cleaning and scented products is associated with nocturnal cough among children and an association between prenatal use of scented Products and mental health comorbidities among children is suggested. Expand
Proximity to Major Roads and Risks of Childhood Recurrent Wheeze and Asthma in a Severe Bronchiolitis Cohort
TLDR
Proximity to major roads is associated with increased risks of recurrent wheeze and asthma in young children and respiratory outcomes were investigated using multivariable Cox proportional hazards modeling and logistic regression, adjusted for confounders. Expand
Onset and remission of childhood wheeze and rhinitis across China - Associations with early life indoor and outdoor air pollution.
TLDR
Outdoor PM2.5, PM10 and NO2 can increase childhood wheeze and rhinitis, and Crowdedness, cockroaches at home and emissions from new building materials and gas cooking can be risk factors for wheez and Rhinitis. Expand
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References

SHOWING 1-10 OF 54 REFERENCES
Exposure to traffic-related air pollution and risk of development of childhood asthma: A systematic review and meta-analysis.
TLDR
The hypothesis that childhood exposure to TRAP contributes to their development of asthma is supported, as the overall risk estimates from the meta-analyses showed statistically significant associations for BC, NO2, PM2.5, PM10 exposures and risk of asthma development. Expand
Effect of outdoor air pollution on asthma exacerbations in children and adults: Systematic review and multilevel meta-analysis
TLDR
This meta-analysis provides evidence of the association between selected air pollutants and asthma exacerbations for different lags, and in children, the association was significant for NO2, SO2 and PM2.5. Expand
Exposure to bisphenol A and the development of asthma: A systematic review of cohort studies.
TLDR
The mean prenatal BPA was associated with the risk of childhood wheeze/asthma and the influence of BPA exposure during the second trimester of pregnancy on the prevalence of childhoodWheeze was marked and further studies are urgently needed to explore the underlying mechanism about adverse effect of B PA exposure on childhood wheEze/ asthma. Expand
Air pollution exposure during pregnancy and infancy and childhood asthma
TLDR
There is no evidence suggesting that the vehicle exhaust level at home during gestation or infancy, using NO x as a proxy, is associated with the risk of childhood asthma, but there is a tendency that moving to a residence with higher concentrations than the first was associated with an increased risk for asthma. Expand
Prenatal exposures and the development of childhood wheezing illnesses
TLDR
Several common potentially modifiable prenatal exposures appear to be consistently associated with childhood wheezing illnesses (e.g. parental smoking, outdoor air pollution, and maternal stress), however, the effect of many other prenatal exposures on the onset of childhood wheazing illnesses remains unclear. Expand
The health burden of pollution: the impact of prenatal exposure to air pollutants
  • S. Vieira
  • Medicine
  • International journal of chronic obstructive pulmonary disease
  • 2015
TLDR
Primary scientific evidence of the effects of air pollution during pregnancy and the impact of these effects on the fetus, infant health, and in particular, the respiratory system is analyzed. Expand
Effect of Early Life Exposure to Air Pollution on Development of Childhood Asthma
TLDR
A statistically significantly increased risk of asthma diagnosis with increased early life exposure to CO, NO, NO2, PM10, SO2, and black carbon is observed and the hypothesis that early childhood exposure to air pollutants plays a role in development of asthma is supported. Expand
Prenatal Particulate Air Pollution and Asthma Onset in Urban Children. Identifying Sensitive Windows and Sex Differences.
TLDR
Higher prenatal PM2.5 exposure at midgestation was associated with asthma development by age 6 years in boys, and distributed lag models adjusting for child age, sex, and maternal factors showed that increased exposure levels at 16-25 weeks gestation were significantly associated with early childhood asthma development. Expand
Exposure to air pollution and development of asthma and rhinoconjunctivitis throughout childhood and adolescence: a population-based birth cohort study.
TLDR
Exposure to air pollution early in life might contribute to the development of asthma throughout childhood and adolescence, particularly after age 4 years, when asthma can be more reliably diagnosed. Expand
Separate and joint effects of tranplacental and postnatal inhalatory exposure to polycyclic aromatic hydrocarbons: Prospective birth cohort study on wheezing events
TLDR
It appears that prenatal PAH exposure may precipitate and intensify early onset of wheezing symptoms in childhood, resulting from the postnatal exposure and suggest that success in reducing the incidence of respiratory diseases in children would depend on reducing both fetal and childhood exposure to air pollution. Expand
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