The impact of nicotine on bone healing and osseointegration.

@article{Balatsouka2005TheIO,
  title={The impact of nicotine on bone healing and osseointegration.},
  author={Dimitra Balatsouka and Klaus Gotfredsen and Christian Lindh and Tord Berglundh},
  journal={Clinical oral implants research},
  year={2005},
  volume={16 3},
  pages={268-76}
}
OBJECTIVES To examine the short-term effect of nicotine on bone healing and osseointegration. MATERIAL AND METHODS Sixteen female rabbits were divided into two groups. The test group was exposed to nicotine tartrate for 8 weeks and the control group was exposed to placebo. Nicotine or placebo was administered via a miniosmotic pump and plasma cotinine levels were measured weekly. The pump delivered 15 mg of nicotine/day for the animals in the test group. All rabbits had three tibial bone… CONTINUE READING

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