The impact of neocyte transfusion in the management of thalassaemia.

  title={The impact of neocyte transfusion in the management of thalassaemia.},
  author={Th. Spanos and Vassilis A Ladis and Fani Palamidou and Ioannis Papassotiriou and A Banagi and Evangelos Premetis and Christos C Kattamis},
  journal={Vox sanguinis},
  volume={70 4},
Transfusional iron overload leading to cardiopathy and other severe complications continues to be a major problem in chronically transfused homozygous beta-thalassaemia patients. It is well known that young red cells (neocytes) survive longer after transfusion and therefore may contribute to the extension of the intervals between transfusions. We evaluated the impact of neocytes in the total annual blood requirements and consequently the transfusional iron load in 18 thalassaemia patients. A… CONTINUE READING