The impact of megakaryocyte proliferation of the evolution of myelofibrosis. Histological follow-up study in 186 patients with chronic myeloid leukaemia.

@article{Buhr1992TheIO,
  title={The impact of megakaryocyte proliferation of the evolution of myelofibrosis. Histological follow-up study in 186 patients with chronic myeloid leukaemia.},
  author={Thomas A. Buhr and Harald Choritz and Axel Georgii},
  journal={Virchows Archiv. A, Pathological anatomy and histopathology},
  year={1992},
  volume={420 6},
  pages={473-8}
}
A histological study on sequential bone marrow biopsies in patients with chronic myeloid leukaemia (CML) was performed. We wished to answer the question as to whether a different content of megakaryopoiesis in the bone marrow of CML patients has a prognostic significance for the development of myelofibrosis during the course of disease. In addition, the… CONTINUE READING