The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status in mice

@inproceedings{Wehrle2015TheIO,
  title={The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status in mice},
  author={Esther Wehrle and Astrid Liedert and Aline Heilmann and Tim Wehner and Ronny Bindl and Lena Fischer and Melanie Haffner-Luntzer and Franz Jakob and Thorsten Schinke and Michael Amling and Anita Ignatius},
  booktitle={Disease models & mechanisms},
  year={2015}
}
Fracture healing is impaired in aged and osteoporotic individuals. Because adequate mechanical stimuli are able to increase bone formation, one therapeutical approach to treat poorly healing fractures could be the application of whole-body vibration, including low-magnitude high-frequency vibration (LMHFV). We investigated the effects of LMHFV on fracture healing in aged osteoporotic mice. Female C57BL/6NCrl mice (n=96) were either ovariectomised (OVX) or sham operated (non-OVX) at age 41 weeks… CONTINUE READING
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