The impact of ischemic intervals on neuromuscular recovery in a porcine (Sus scrofa) survival model of extremity vascular injury.

@article{Burkhardt2011TheIO,
  title={The impact of ischemic intervals on neuromuscular recovery in a porcine (Sus scrofa) survival model of extremity vascular injury.},
  author={Gabriel E. Burkhardt and Shaun M. Gifford and Brandon W. Propper and Jerry Richard Spencer and Ken Williams and L. Kimberly Jones and Nathan S Sumner and Jerry R. Cowart and Todd E. Rasmussen},
  journal={Journal of vascular surgery},
  year={2011},
  volume={53 1},
  pages={
          165-73
        }
}
BACKGROUND Despite advances in revascularization following extremity vascular injury, the relationship between time to restoration of flow and functional limb salvage is unknown. The objectives of this study are to describe a large animal survival model of hind limb ischemia/reperfusion and define neuromuscular recovery following increasing ischemic periods. METHODS Sus scrofa swine (N = 38; weight, 87 ± 6.2 kg) were randomized to iliac artery occlusion for 0 (Control), 1 (1HR), 3 (3HR), or 6… CONTINUE READING
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