The impact of immunosuppressive drugs on the analysis of T cell activation.

@article{Rovira2000TheIO,
  title={The impact of immunosuppressive drugs on the analysis of T cell activation.},
  author={P Soler Rovira and Laurent Mascarell and P Truffa-bachi},
  journal={Current medicinal chemistry},
  year={2000},
  volume={7 7},
  pages={
          673-92
        }
}
The discovery of the immunosuppressive properties of cyclosporin A (CSA) and its successful utilisation in organ transplantation was a milestone in clinics. CSA has revolutionised transplantation both in term of efficiency and quality-of-life of the patient. In addition, the analysis of the mode of action of CSA has been rewarding in the understanding the mechanisms leading to T lymphocytes activation. CSA binds to a family of cytosolic receptors, the cyclophilins, a highly conserved family of… CONTINUE READING
21 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…