The impact of ibuprofen on renal clearance in preterm infants is independent of the gestational age

@article{Allegaert2005TheIO,
  title={The impact of ibuprofen on renal clearance in preterm infants is independent of the gestational age},
  author={Karel Allegaert and Veerle R Cossey and Anne Debeer and Jean Paul Langhendries and Bart Van Overmeire and Jan de Hoon and Hugo Devlieger},
  journal={Pediatric Nephrology},
  year={2005},
  volume={20},
  pages={740-743}
}
The aim of this investigation was to evaluate whether the relative change in renal clearance due to ibuprofen administration depends on the gestational age (GA). Clearance of amikacin was used as a surrogate marker for renal clearance in preterm infants (GA 24–34 weeks, day 1) on respiratory support. Clearance in infants co-treated with ibuprofen was… CONTINUE READING