The impact of high density receptor clusters on VEGF signaling

@article{Chen2013TheIO,
  title={The impact of high density receptor clusters on VEGF signaling},
  author={Ye Chen and Christopher Short and {\'A}d{\'a}m M. Hal{\'a}sz and Jeremy S. Edwards},
  journal={Electronic proceedings in theoretical computer science},
  year={2013},
  volume={2013},
  pages={37-52}
}
Vascular endothelial growth factor (VEGF) signaling is involved in the process of blood vessel development and maintenance. Signaling is initiated by binding of the bivalent VEGF ligand to the membrane-bound receptors (VEGFR), which in turn stimulates receptor dimerization. Herein, we discuss experimental evidence that VEGF receptors localize in caveloae… CONTINUE READING