The impact of gap duration on local control in anal canal carcinoma treated by split-course radiotherapy and concomitant chemotherapy.

@article{Weber2001TheIO,
  title={The impact of gap duration on local control in anal canal carcinoma treated by split-course radiotherapy and concomitant chemotherapy.},
  author={Damien Charles Weber and John M. Kurtz and Abdelkarim Said Allal},
  journal={International journal of radiation oncology, biology, physics},
  year={2001},
  volume={50 3},
  pages={675-80}
}
PURPOSE To investigate the potential benefit of reducing the intersequence gap in patients with anal cancer treated with split-course chemoradiotherapy. METHODS The study group consisted of 90 patients with anal squamous carcinoma treated between 1981 and 1998, using concomitant chemotherapy (CT) and radiation (RT). Median age was 65 years (range 41-87). RT was delivered in a split course, with a median gap of 37.5 days (range 4-97) between sequences. First (pelvic) sequence delivered a… CONTINUE READING
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