The impact of early adverse care on HPA axis development: Nonhuman primate models

@article{Sanchez2006TheIO,
  title={The impact of early adverse care on HPA axis development: Nonhuman primate models},
  author={Mar M. Sanchez},
  journal={Hormones and Behavior},
  year={2006},
  volume={50},
  pages={623-631}
}
  • M. Sanchez
  • Published 1 November 2006
  • Psychology, Biology
  • Hormones and Behavior
The Neurobiology of Intervention and Prevention in Early Adversity.
TLDR
The research on three neurobiological systems relevant to interventions for populations experiencing high levels of early adversity are summarized: the hypothalamic-adrenal-pituitary axis, the prefrontal cortex regions involved in executive functioning, and the system involved in threat detection and response, particularly the amygdala.
Nonhuman primate models of depression: effects of early experience and stress.
TLDR
The NHP offers an excellent model to research mechanisms contributing to the Diathesis-Stress/Two-Hit model of depression, and is reviewed to provide examples of how this model has been used to investigate the effects of early experience on later neurobiology, physiology, and behavior associated with depression.
Social buffering of stress responses in nonhuman primates: Maternal regulation of the development of emotional regulatory brain circuits
TLDR
Taking advantage of this naturalistic animal model of adverse maternal caregiving, it is shown that competent maternal care is critical for the development of healthy attachment, social behavior, and emotional and stress regulation, as well of the neural circuits underlying these functions.
arly life adversity during the infant sensitive period for attachment : rogramming of behavioral neurobiology of threat processing and ocial behavior
TLDR
The interaction between trauma and attachment during a sensitive period in early life is described, which highlights the role of the caregiver’s presence in engagement of attachment brain circuitry and suppressing threat pro-actively.
Developmental outcomes of early adverse care on amygdala functional connectivity in nonhuman primates
TLDR
The developmental impact of maltreatment on amygdala functional connectivity (FC) longitudinally, from infancy through the juvenile period, may underlie the poor behavioral outcomes associated with this adverse experience of infant maltreatment.
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  • D. Maestripieri
  • Psychology, Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2005
TLDR
Results suggest that the intergenerational transmission of infant abuse in rhesus monkeys is the result of early experience and not genetic inheritance, and the extent to which the effects ofEarly experience on the intergeneration transmission of abusive parenting are mediated by social learning or experience-induced physiological alterations remains to be established.
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