Corpus ID: 35995729

The impact of chemotherapy-induced nausea and vomiting.

  title={The impact of chemotherapy-induced nausea and vomiting.},
  author={Gary R. Morrow},
  journal={Clinical advances in hematology \& oncology : H\&O},
  volume={12 Suppl 9 3},
  • G. Morrow
  • Published 1 March 2014
  • Medicine
  • Clinical advances in hematology & oncology : H&O
Chemotherapy-induced nausea and vomiting (CINV) has a broad range of consequences that can affect not only the patient’s general health status but also daily function and quality of life. Patients undergoing chemotherapy should be encouraged to maintain adequate nutritional and fluid intake to prevent the weight loss, electrolyte imbalances, and dehydration that can result from CINV. Patients also should be monitored closely for signs and symptoms of these problems because early intervention… Expand
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Chemotherapy-induced nausea and vomiting (CINV) can have a myriad of clinical consequences for patients, their families, and the healthcare system, including early treatment discontinuation; nonadherence to chemotherapy treatment; problems with appetite and eating; and higher direct and indirect costs of care. Expand
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Chemotherapy-induced nausea and vomiting.
The state of the science related to chemotherapy-induced nausea and vomiting is examined and both pharmacologic and behavioral strategies that have demonstrated efficacy in managing these distressing symptoms are reviewed. Expand
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Patients about to receive moderately or highly emetogenic chemotherapy should be screened for these factors and additional measures, such as behavior modification and modification of antiemetic therapy, should be considered in attempts to improve the control of PCNV. Expand
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PCNV adversely affects several quality-of-life domains, but patients with only nausea experience less disruption than do those with both nausea and vomiting, and by 2–4 weeks after chemotherapy all HQL scores had either returned to their baseline levels or were better than baseline. Expand
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The pattern between the younger and older patients' N, V, and R subscale scores was consistent in that the younger patients' scores were consistently (except on one occasion) higher than the older Patients' scores, but this difference was statistically insignificant. Expand
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The authors determined the incidence of acute and delayed chemotherapy‐induced nausea and emesis (vomiting) (CINV) among patients receiving highly (HEC) or moderately (MEC) emetogenic chemotherapy.Expand
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Our understanding of the pathophysiology of emesis has improved over the past 2 decades, and we now have drugs that can prevent acute emesis in most patients. Prevention and treatment of the delayedExpand