The impact of carbon dioxide and helium insufflation on experimental liver metastases, macrophages, and cell adhesion molecules

Abstract

Background: Laparoscopic insufflation, proposed to reduce hepatic perfusion, may enhance hepatic tumor spread. It is unknown whether intraabdominal pressure or the gas itself influences hepatic tumor growth. In contrast to carbon dioxide, the alternative gas helium is believed to reduce malignant cell growth. Methods: For this study, 36 WAG/Rij rats were… (More)
DOI: 10.1007/s00464-002-9228-5

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