The impact of alcoholism on sleep evoked Delta frequency responses.

  title={The impact of alcoholism on sleep evoked Delta frequency responses.},
  author={Ian M. Colrain and Kate E. Crowley and Christian Luke Nicholas and Mayra L. Padilla and Fiona C. Baker},
  journal={Biological psychiatry},
  volume={66 2},
BACKGROUND K-complexes (KCs) are evoked delta frequency electroencephalogram (EEG) responses during sleep that occur when large numbers of healthy cortical cells burst fire in a synchronized manner. The KC amplitude and incidence are sensitive measures of normal healthy brain aging. Given the known neurodegenerative consequences of alcohol abuse it was hypothesized that alcoholism would be associated with further KC amplitude and incidence reductions. METHODS Eighty-four subjects (42… CONTINUE READING


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