The impact of HLA matching on long-term transplant outcome after allogeneic hematopoietic stem cell transplantation for CLL: a retrospective study from the EBMT registry

@article{Michallet2010TheIO,
  title={The impact of HLA matching on long-term transplant outcome after allogeneic hematopoietic stem cell transplantation for CLL: a retrospective study from the EBMT registry},
  author={Mauricette Michallet and Mohamad A Sobh and D. K. Milligan and St{\'e}phane Morisset and Dietger Niederwieser and Vladim{\'i}r Koza and Tapani Ruutu and Nigel H. Russell and Leo F. Verdonck and Nathalie Dh{\'e}din and Anton{\'i}n V{\'i}tek and Marc A. Boogaerts and Lars L. Vindelov and J{\"u}rgen M Finke and V. N. Vleesch Dubois and Anja van Biezen and Ronald Brand and T de Witte and Peter Dreger},
  journal={Leukemia},
  year={2010},
  volume={24},
  pages={1725-1731}
}
We analyzed 368 chronic lymphocytic leukemia patients who underwent allogeneic hematopoietic stem cell transplantation reported to the EBMT registry between 1995 and 2007. There were 198 human leukocyte antigen (HLA)-identical siblings; among unrelated transplants, 31 were well matched in high resolution (‘well matched’ unrelated donor, WMUD), and 139 were mismatched (MM), including 30 matched in low resolution; 266 patients (72%) received reduced-intensity conditioning and 102 (28%) received… CONTINUE READING