The impact of DNA twisting and bending rigidity on protein – induced looping dynamics

  • Published 2012
Protein–induced DNA looping is a key regulatory mechanism involved in important processes such as transcription, gene regulation and replication. The relationship between the induced loop topology and DNA–protein dynamics is essential for understanding these processes. Here, we use tethered–particle motion (TPM) to examine the impact of bending and twisting… (More)