The impact of C-MYC gene expression on gastric cancer cell

  title={The impact of C-MYC gene expression on gastric cancer cell},
  author={Lin Zhang and Yanhong Hou and Hassan Ashktorab and Liucun Gao and Yanjie Xu and Kai Wu and Junshan Zhai and Lei Zhang},
  journal={Molecular and Cellular Biochemistry},
The upregulation or mutation of C-MYC has been observed in gastric, colon, breast, and lung tumors and in Burkitt’s lymphoma. However, little is known about the role C-MYC plays in gastric adenocarcinoma. In the present study, we intended to investigate the influence of C-MYC on the growth, proliferation, apoptosis, invasion, and cell cycle of the gastric cancer cell line SGC7901 and the gastric cell line HFE145. C-MYC cDNA was subcloned into a constitutive vector PCDNA3.1 followed by… CONTINUE READING


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