The immunosuppressive signature of menstrual blood mesenchymal stem cells entails opposite effects on experimental arthritis and graft versus host diseases.

@article{LuzCrawford2016TheIS,
  title={The immunosuppressive signature of menstrual blood mesenchymal stem cells entails opposite effects on experimental arthritis and graft versus host diseases.},
  author={P Luz-Crawford and Mar{\'i}a Jos{\'e} Alvarez Torres and Dani{\'e}le No{\"e}l and Ainoa Fernandez and Karine Toupet and Francisca Alcayaga-Miranda and Gautier Tejedor and Christian Jorgensen and Sebasti{\'a}n E Illanes and F E Figueroa and Farida Djouad and Maroun D. Khoury},
  journal={Stem cells},
  year={2016},
  volume={34 2},
  pages={456-69}
}
Recently, a noninvasive and highly proliferative stem cell population from menstrual blood called MenSCs has been identified. Despite their use in clinical studies, their immunomodulatory properties have not yet been investigated. In this context, we studied the immunosuppressive properties of MenSCs in comparison with the well-characterized bone marrow derived-MSCs (BM-MSCs). Using an in vitro proliferation assays, we showed that MenSCs displayed a lower suppressive effect on peripheral blood… CONTINUE READING
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