The immunophenotype of splenic lymphoma with villous lymphocytes and its relevance to the differential diagnosis with other B-cell disorders.

@article{Matutes1994TheIO,
  title={The immunophenotype of splenic lymphoma with villous lymphocytes and its relevance to the differential diagnosis with other B-cell disorders.},
  author={Estella Matutes and Ricardo M Morilla and Kwasi A Owusu-Ankomah and Adam J. Houlihan and Daniel Catovsky},
  journal={Blood},
  year={1994},
  volume={83 6},
  pages={1558-62}
}
Splenic lymphoma with villous lymphocytes (SLVL) is a low-grade disorder that regularly presents with peripheral blood involvement. We describe the immunophenotype of the circulating cells from 100 SLVL patients whose disease has been characterized on clinical, morphologic, and histologic grounds. Cells from all cases expressed B-cell antigens (CD19 and CD37) and/or HLA-Dr and showed light chain restriction (kappa/lambda: 1.5/1) with moderate to strong intensity of membrane Ig staining. Cells… CONTINUE READING

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  • L Visser, A Shaw, J Slupsky, H Voss, S Poppema
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