The immunomodulator decoy receptor 3 improves locomotor functional recovery after spinal cord injury

@inproceedings{Chiu2016TheID,
  title={The immunomodulator decoy receptor 3 improves locomotor functional recovery after spinal cord injury},
  author={Chuan-Wen Chiu and W H Huang and Shao-Ji Lin and M J Tsai and Hsu Ma and Shie-Liang Hsieh and Henrich Cheng},
  booktitle={Journal of Neuroinflammation},
  year={2016}
}
Spinal cord injury (SCI) causes loss of neurons and axons and results in motor and sensory function impairments. SCI elicits an inflammatory response and induces the infiltration of immune cells, predominantly macrophages, to the injured site. Decoy receptor 3 (DcR3), also known as tumor necrosis factor receptor superfamily member (TNFRSF)-6B, is a pleiotropic immunomodulator capable of inducing macrophage differentiation into the M2 phenotype and enhancing angiogenesis. Because M2 macrophages… CONTINUE READING
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