The immunology of sepsis.

  title={The immunology of sepsis.},
  author={Shiranee Sriskandan and Daniel M. Altmann},
  journal={The Journal of pathology},
  volume={214 2},
Sepsis, the systemic inflammatory response to infection, is considered the major cause of death among critically ill patients in the developed world. While there is a general view that this reflects contributions from both the pathogen and the host with respect to an inappropriate inflammatory response, there is a lack of agreement as to the key immune mechanisms. This has been reflected in the diverse range of immunotherapies tested in clinical trials, often with rather marginal effects. The… CONTINUE READING


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