The immunology of asthma

@article{Lambrecht2014TheIO,
  title={The immunology of asthma},
  author={B. Lambrecht and H. Hammad},
  journal={Nature Immunology},
  year={2014},
  volume={16},
  pages={45-56}
}
Asthma is a common disease that affects 300 million people worldwide. Given the large number of eosinophils in the airways of people with mild asthma, and verified by data from murine models, asthma was long considered the hallmark T helper type 2 (TH2) disease of the airways. It is now known that some asthmatic inflammation is neutrophilic, controlled by the TH17 subset of helper T cells, and that some eosinophilic inflammation is controlled by type 2 innate lymphoid cells (ILC2 cells) acting… Expand
Myeloid Cells in Asthma.
An Update on Lymphocyte Subtypes in Asthma and Airway Disease
Eosinophil diversity in asthma.
The Cytokines of Asthma.
The diverse roles of T cell subsets in asthma.
Mouse Models of Asthma
T Cells in Allergic Asthma: Key Players Beyond the Th2 Pathway
Innate-like Lymphocytes and Innate Lymphoid Cells in Asthma
Mimicking Antigen-Driven Asthma in Rodent Models—How Close Can We Get?
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References

SHOWING 1-10 OF 196 REFERENCES
The airway epithelium in asthma
Epithelial interleukin-25 is a key mediator in Th2-high, corticosteroid-responsive asthma.
Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma.
T-helper type 2-driven inflammation defines major subphenotypes of asthma.
IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways.
...
1
2
3
4
5
...