The immunological milieu of the liver.

  title={The immunological milieu of the liver.},
  author={Carlo Selmi and Ian R. Mackay and M Eric Gershwin},
  journal={Seminars in liver disease},
  volume={27 2},
From the immunology standpoint, the liver is a peculiar organ for several reasons that range from its anatomical location to its cytoarchitecture and its variety of specific functions. Receiving blood directly from the digestive system, the liver is the crossroad at which the majority of antigens enter the organism. Hence, the milieu of the liver must provide a finely tuned balance between generating tolerance to self as well as to nonpathogenic molecules and microorganisms and producing an… CONTINUE READING

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