The immunohistochemical assessment of hypoxia, vascularity and proliferation in bladder carcinoma.


BACKGROUND AND PURPOSE Hypoxia and proliferation are important determinants of radiation responsiveness; prospective measures of these before radiotherapy may enable individualisation of treatment schedules. Immunohistochemical techniques offer a potential means of achieving this in routine biopsy material. MATERIAL AND METHODS Cellular hypoxia as… (More)


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