The immunogenicity and safety of an investigational meningococcal serogroups A, C, W-135 and Y tetanus toxoid conjugate vaccine (ACWY-TT) compared with a licensed meningococcal tetravalent polysaccharide vaccine

@inproceedings{Dbaibo2012TheIA,
  title={The immunogenicity and safety of an investigational meningococcal serogroups A, C, W-135 and Y tetanus toxoid conjugate vaccine (ACWY-TT) compared with a licensed meningococcal tetravalent polysaccharide vaccine},
  author={Ghassan S. Dbaibo and Noel G. Macalalad and Mari Rose Aplasca-De Los Reyes and Efren M. Dimaano and V{\'e}ronique Bianco and Yaela Baine and Jacqueline Miller},
  booktitle={Human vaccines & immunotherapeutics},
  year={2012}
}
Immunogenicity and safety of ACWY-TT compared with licensed ACWY polysaccharide vaccine (MenPS) in healthy adults, and lot-to-lot consistency of three ACWY-TT lots were evaluated in a phase 3, open, controlled study. Adults aged 18-55 y were randomized to receive ACWY-TT (one of three lots) or MenPS. Serum bactericidal antibodies (rSBA) were measured pre- and 1 mo post-vaccination. Adverse events (AEs) were assessed 4 d (solicited symptoms) and 31 d (unsolicited symptoms) post-vaccination… CONTINUE READING

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Summary of the National Advisory Committee on Immunization's Update on quadrivalent meningococcal vaccines available in Canada.

Canada communicable disease report = Releve des maladies transmissibles au Canada • 2015

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