The immunoexpression of Shh, Smo and Gli2 in Helicobacter pylori positive and negative gastric biopsies.

@article{StasikowskaKanicka2012TheIO,
  title={The immunoexpression of Shh, Smo and Gli2 in Helicobacter pylori positive and negative gastric biopsies.},
  author={Olga Stasikowska-Kanicka and M Wagrowska-Danilewicz and Iwona Białek and Marian Danilewicz},
  journal={Polish journal of pathology : official journal of the Polish Society of Pathologists},
  year={2012},
  volume={63 1},
  pages={25-30}
}
The Hedgehog signaling pathway plays a principal role during embryonic development, tissue regeneration and carcinogenesis in various adult tissues. Although hedgehog signaling is important in gastric carcinogenesis, its role in Helicobacter pylori-associated gastritis is unclear. The aim of our study was to examine Sonic Hedgehog (Shh) signaling pathway in response to H. pylori infection. Thirty-one formalin-fixed, paraffin-embedded tissue specimens of chronic gastritis were retrieved from… CONTINUE READING