The immune system of cyprinid fish. Oxytetracycline and the regulation of humoral immunity in carp (Cyprinus carpio).

@article{Rijkers1981TheIS,
  title={The immune system of cyprinid fish. Oxytetracycline and the regulation of humoral immunity in carp (Cyprinus carpio).},
  author={Ger T. Rijkers and Rolinda van Oosterom and Willem B. Van Muiswinkel},
  journal={Veterinary immunology and immunopathology},
  year={1981},
  volume={2 3},
  pages={281-90}
}
The antibiotic oxytetracycline (oxyTC) was administered either by mixing with food or by intraperitoneal injections. On oxyTC treated animals decreased serum immunoglobulin levels were found. The primary anti-sheep red blood cells (SRBC) response was measured by enumerating plaque forming cells (PFC). It was observed that the PFC response was depressed by 80-95% in oxyTC treated animals. When an anti-SRBC serum was injected together with SRBC the immunosuppressive effect of oxyTC was absent. A… CONTINUE READING

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