The immune system in critical illness.

  title={The immune system in critical illness.},
  author={John C. Marshall and Emmanuel Charbonney and Patricia Gonz{\'a}lez},
  journal={Clinics in chest medicine},
  volume={29 4},
  pages={605-16, vii}
The mammalian immune system comprises a complex network of physical and molecular elements that protect the individual from danger in the environment. An evolutionarily ancient innate immune system recognizes danger through pattern-recognition receptors that are encoded in the genome and mobilizes a rapid and potent but nonspecific response. This response is responsible for the clinical syndromes of sepsis and the multiple organ dysfunction syndrome. The adaptive immune system is highly… CONTINUE READING

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