The immune system in aging: roles of cytokines, T cells and NK cells.

@article{Huang2005TheIS,
  title={The immune system in aging: roles of cytokines, T cells and NK cells.},
  author={Hai Huang and Dhavalkumar D. Patel and Kenneth G. Manton},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2005},
  volume={10},
  pages={192-215}
}
Aging is characterized by a proinflammatory state that contributes to the onset of disability and age-related diseases. Proinflammatory cytokines play a central role in mediating cellular and physiological responses. The levels of these cytokines may reflect immune system effectiveness. Studies of the effects of aging on inflammatory response show interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) to be important. In this review, age-related changes… CONTINUE READING

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