The immune status of Kupffer cells profoundly influences their responses to infectious Plasmodium berghei sporozoites.

@article{Steers2005TheIS,
  title={The immune status of Kupffer cells profoundly influences their responses to infectious Plasmodium berghei sporozoites.},
  author={Nick Steers and Robert J. Schwenk and David J. Bacon and Dmitri Berenzon and Jackie Williams and Urszula Krzych},
  journal={European journal of immunology},
  year={2005},
  volume={35 8},
  pages={2335-46}
}
Multi-factorial immune mechanisms underlie protection induced with radiation-attenuated Plasmodia sporozoites (gamma-spz). Spz pass through Kupffer cells (KC) before invading hepatocytes but the involvement of KC in protection is poorly understood. In this study we investigated whether gamma-spz-immune KC respond to infectious spz in a manner that is distinct from the response of naive KC to infectious spz. KC were isolated from (1) naive, (2) spz-infected, (3) gamma-spz-immune, and (4) gamma… CONTINUE READING
Highly Cited
This paper has 44 citations. REVIEW CITATIONS
16 Citations
35 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Similar Papers

Loading similar papers…