The immune response to apoptotic cells.

  title={The immune response to apoptotic cells.},
  author={Dror Mevorach},
  journal={Annals of the New York Academy of Sciences},
  • Dror Mevorach
  • Published 1999 in Annals of the New York Academy of Sciences
Programmed cell death (PCD) can be divided into two distinct but linked sequential processes, killing of the cells and removal of the dead cells, which may be a neighboring cell or a professional phagocyte. Following internalization of the apoptotic cell, the phagocyte typically triggers neither the development of a pro-inflammatory response nor the production of autoantibodies directed against apoptotic self antigens. Since apoptotic cells are characterized by translocation of autoantigens… CONTINUE READING