The immune microenvironment of human fracture/soft-tissue hematomas and its relationship to systemic immunity.

@article{Hauser1997TheIM,
  title={The immune microenvironment of human fracture/soft-tissue hematomas and its relationship to systemic immunity.},
  author={Carl J. Hauser and X Zhou and Preeti Avinash Joshi and Marvin A. Cuchens and Philip James Kregor and Meenakshi Devidas and R J Kennedy and Galen V. Poole and Jennifer L. Hughes},
  journal={The Journal of trauma},
  year={1997},
  volume={42 5},
  pages={895-903; discussion 903-4}
}
The immune environment of human soft-tissue injury is unstudied. We studied fracture soft-tissue hematomas (FxSTH) in 56 patients with high-energy bony fractures. FxSTH serum and mononuclear cells (MNC) as well as fracture patient plasma and blood MNC were studied. Twenty healthy controls donated plasma and MNC. Soluble tumor necrosis factor (TNF)-alpha, interleukin (IL-1 beta, IL-2, 6, 8, 10, 12, and interferon-gamma were studied by enzyme linked immunosorbent assay. Cells were studied by flow… CONTINUE READING

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