The illusion of evidence based medicine

  title={The illusion of evidence based medicine},
  author={Jon Jureidini and Leemon B. McHenry},
Evidence based medicine has been corrupted by corporate interests, failed regulation, and commercialisation of academia, argue these authors 

Industry influence in healthcare harms patients: myth or maxim?

Examining interactions with industry across these domains seeks to identify mutually beneficial relationships and potential conflict leading to patient harms and explores the many areas where industry influences healthcare and the subsequent effects on patient care.

Mass versus personalized medicine against COVID-19 in the "system sciences" era.

The current landscape of personalized medicine approaches against SARS-CoV-2 is discussed and a schematic of the approach is illustrated in the figure in the text.

A Proposal to Increase Value and Equity in the Development and Distribution of New Pharmaceuticals

A new agency of the Food and Drug Administration (FDA) would fund the research and development of high-value medications, closely monitor the clinical studies of these new drugs, and manage their distribution at prices that are value-based, fair, and equitable.

Why Community Health Systems Have Not Flourished in High Income Countries: What the Australian Experience Tells Us.

  • F. BaumT. Freeman
  • Political Science, Medicine
    International journal of health policy and management
  • 2021
The study of the community health system in Australia indicates that instituting such a system in high income countries will require systematic ideological, political and institutional change to shift the overarching government policy environment, and health sector policies and practices towards a social model of health which allows community control, and multidisciplinary service provision.

Chest Drainage Therapy: What Comes out of Pandora’s Box Can Affect Patient Outcomes

Different chest drainage unit designs lead to different performances, some of which may negatively impact patient outcomes, which sounds the call to tailor the authors' clinical practice for the individual patient.

Pandemic of misinformation

This article is dedicated to clearing up (to whatever extent and reach I have) this "pandemic of misinformation" regarding COVID-19.

Decolonizing Knowledge Upstream: New Ways to Deconstruct and Fight Disinformation in an Era of COVID-19, Extreme Digital Transformation, and Climate Emergency.

Lies and disinformation have always existed throughout human history. However, disinformation has become a "pandemic within a pandemic" with convergence of COVID-19 and digital transformation of

Cientificismo y trastorno por déficit de atención e hiperactividad (TDAH)

Para que un diagnostico como el trastorno por deficit de atencion e hiperactividad (TDAH) sea util cientificamente, es necesario demostrar que el concepto conduce a un avance del conocimiento en

Challenging pharma: who cares?



Clinical trials and drug promotion: Selective reporting of study 329

Documents obtained during litigation reveal that study 329 of paroxetine was negative for efficacy on all 8 protocol specified outcomes and positive for harm.

Biomedical conflicts of interest: a defence of the sequestration thesis—learning from the cases of Nancy Olivieri and David Healy

  • A. Schafer
  • Political Science
    Journal of Medical Ethics
  • 2004
After a literature survey of the ways in which corporate sponsorship has biased the results of clinical drug trials, two different strategies to mitigate this problem are identified and assessed: a regulatory approach, which focuses on managing risks associated with industry funding of university research, and a more radical approach, the sequestration thesis, which counsels the outright elimination of corporate sponsorship.

Pandemrix vaccine: why was the public not told of early warning signs?

  • P. Doshi
  • Medicine
    British Medical Journal
  • 2018
Eight years after the pandemic influenza outbreak, a lawsuit alleging that GlaxoSmithKline’s Pandemrix vaccine caused narcolepsy has unearthed internal reports suggesting problems with the vaccine’s

Exploring the Asymmetrical Relationship Between the Power of Finance Bias and Evidence

  • J. Howick
  • Economics
    Perspectives in biology and medicine
  • 2019
For EBM to be effective, the power of finance bias influencing the production and dissemination of evidence needs to be addressed as a priority, with initiatives such as the AllTrials campaign, which identifies and exposes unpublished trials.

Narrative Review: The Promotion of Gabapentin: An Analysis of Internal Industry Documents

How marketing strategies and tactics for gabapentin were developed and used in the mid- and late 1990s are described, focusing on how certain groups of physicians were targeted as recipients of and vehicles for promotion.

The Poverty of Historicism

On its publication in 1957, The Poverty of Historicism was hailed by Arthur Koestler as 'probably the only book published this year which will outlive the century.' A devastating criticism of fixed

Risk of cardiovascular events associated with selective COX-2 inhibitors.

The results from VIGOR showed that the relative risk of developing a confirmed adjudicated thrombotic cardiovascular event with rofecoxib treatment compared with naproxen was higher than that in the placebo group of a recent meta-analysis of 23 407 patients in primary prevention trials.

Universities in the Marketplace: The Commercialization of Higher Education

Is everything in a university for sale if the price is right? In this book, one of America's leading educators cautions that the answer is all too often "yes." Taking the first comprehensive look at

Universities in the marketplace: the commercialization of higher education

Nos ultimos 20 anos, universidades tem mudado seu tradicional foco de formacao para cada vez mais enfatizar ensino e pesquisas multidisciplinares estreitamente relacionadas com finalidades praticas e