The idiopathic hypereosinophilic syndrome: clinical presentation, pathogenesis and therapeutic strategies.

@article{Roufosse1998TheIH,
  title={The idiopathic hypereosinophilic syndrome: clinical presentation, pathogenesis and therapeutic strategies.},
  author={Florence E. Roufosse and Emmanuel Bartholom{\'e} and Liliane Schand{\'e}n{\'e} and Michel Goldman and Elie Cogan},
  journal={Drugs of today},
  year={1998},
  volume={34 4},
  pages={361-73}
}
The idiopathic hypereosinophilic syndrome (HES) is a heterogenous disease entity characterized by persistent unexplained hypereosinophilia generally complicated by end-organ damage. Correct diagnosis and management are important in order to prevent long-term complications. Furthermore, it appears that HES represents a premalignant state in some patients, and close follow-up is necessary to detect early signs of malignant transformation. Previous studies of patient cohorts have led to the… CONTINUE READING