The identity of cells expressing MHC class II antigens in normal and pathological human brain.

@article{Sasaki1992TheIO,
  title={The identity of cells expressing MHC class II antigens in normal and pathological human brain.},
  author={Atsushi Sasaki and Youichi Nakazato},
  journal={Neuropathology and applied neurobiology},
  year={1992},
  volume={18 1},
  pages={13-26}
}
Major histocompatibility complex class II antigen (Ag) expression in human brain was investigated in autopsied human brain tissues, using anti-human class II monoclonal antibodies. In normal brains, class II Ag was usually absent or was low in positivity. When it was found immunohistochemically, it appeared more frequently in the meninges (meningeal macrophages) and the neurohypophysis (pituicytes) than in the cerebral cortex (microglia and perivascular cells). The identity of the latter cell… CONTINUE READING

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