The identification of secreted carbonic anhydrase VI as a constitutive glycoprotein of human and rat milk.

@article{Karhumaa2001TheIO,
  title={The identification of secreted carbonic anhydrase VI as a constitutive glycoprotein of human and rat milk.},
  author={P Karhumaa and Jukka S Leinonen and Seppo Parkkila and Kari Kaunisto and Juha Tapanainen and Hannu Rajaniemi},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2001},
  volume={98 20},
  pages={11604-8}
}
In addition to essential nutrients, human milk contains several classes of bioactive factors such as enzymes, hormones, and growth factors, many of which are implicated in infantile growth and development. Secretory carbonic anhydrase isoenzyme VI (CA VI) has been identified earlier as an essential component of mammalian saliva, and we demonstrate here by using biochemical and immunohistochemical techniques that it is also an elementary component of milk. The 42-kDa glycopolypeptide purified… CONTINUE READING