The identification of goat peroxiredoxin-5 and the evaluation and enhancement of its stability by nanoparticle formation

@inproceedings{Feng2016TheIO,
  title={The identification of goat peroxiredoxin-5 and the evaluation and enhancement of its stability by nanoparticle formation},
  author={Xiaozhou Feng and Juanjuan Liu and Shuai Fan and Fan Liu and Yadong Li and Yuanyuan Jin and Liping Bai and Zhaoyong Yang},
  booktitle={Scientific reports},
  year={2016}
}
An anticancer bioactive peptide (ACBP), goat peroxiredoxin-5 (gPRDX5), was identified from goat-spleen extract after immunizing the goat with gastric cancer-cell lysate. Its amino acid sequence was determined by employing 2D nano-LC-ESI-LTQ-Orbitrap MS/MS combined with Mascot database search in the goat subset of the Uniprot database. The recombinant gPRDX5 protein was acquired by heterogeneous expression in Escherichia coli. Subsequently, the anti-cancer bioactivity of the peptide was measured… CONTINUE READING
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The authors declare no competing financial interests

Forte, 31 M.etal.Polystyrenenanoparticlesinternalizationinhu, +15 authors Z.Y.Y. guided all aspects of the work. Additional Informa interests
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