The identification of FANCD2 DNA binding domains reveals nuclear localization sequences

@inproceedings{Niraj2017TheIO,
  title={The identification of FANCD2 DNA binding domains reveals nuclear localization sequences},
  author={Joshi Niraj and Marie-Christine Caron and Karine Drapeau and St{\'e}phanie B{\'e}rub{\'e} and Laure Guitton-Sert and Yan Coulombe and Anthony M Couturier and J Masson},
  booktitle={Nucleic acids research},
  year={2017}
}
Fanconi anemia (FA) is a recessive genetic disorder characterized by congenital abnormalities, progressive bone-marrow failure, and cancer susceptibility. The FA pathway consists of at least 21 FANC genes (FANCA-FANCV), and the encoded protein products interact in a common cellular pathway to gain resistance against DNA interstrand crosslinks. After DNA… CONTINUE READING