The identification and expression of heme oxygenase-2 alternative transcripts in the mouse.

@article{Gibbs1998TheIA,
  title={The identification and expression of heme oxygenase-2 alternative transcripts in the mouse.},
  author={Louise M E Gibbs and Dianna Willis and Megan J Morgan},
  journal={Gene},
  year={1998},
  volume={221 2},
  pages={171-7}
}
Murine heme oxygenase-2 (HO-2) cDNA sequences were determined through the assembly of mouse expressed sequence tag (EST) sequences using the rat HO-2 sequence as a template. The sequence analysis revealed two mRNA isoforms, probably arising through alternative splicing, which differed in their 5'-untranslated region (UTR), and were named HO-2a and HO-2b. One EST sequence included an extended 3'-UTR and suggested there may be a choice of poly-adenylation (poly-A) signal sequence. Reverse… CONTINUE READING

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