The identification and characterization of non-coding and coding RNAs and their modified nucleosides by mass spectrometry

@inproceedings{Gaston2014TheIA,
  title={The identification and characterization of non-coding and coding RNAs and their modified nucleosides by mass spectrometry},
  author={Kirk W. Gaston and Patrick A. Limbach},
  booktitle={RNA biology},
  year={2014}
}
The analysis of ribonucleic acids (RNA) by mass spectrometry has been a valuable analytical approach for more than 25 years. In fact, mass spectrometry has become a method of choice for the analysis of modified nucleosides from RNA isolated out of biological samples. This review summarizes recent progress that has been made in both nucleoside and oligonucleotide mass spectral analysis. Applications of mass spectrometry in the identification, characterization and quantification of modified… CONTINUE READING