The identification and assay of 2-methyl-5-nitroimidazole in pigs treated with dimetridazole.

@article{Carignan1991TheIA,
  title={The identification and assay of 2-methyl-5-nitroimidazole in pigs treated with dimetridazole.},
  author={G. R. Carignan and Kmanuela Carrier and S M Sved},
  journal={Food additives and contaminants},
  year={1991},
  volume={8 4},
  pages={467-75}
}
An unidentified metabolite of dimetridazole (DMZ), found in pig plasma, muscle and kidney, was shown by chromatography and spectroscopy to be 2-methyl-5-nitroimidazole (2-MNI), resulting from N-demethylation of DMZ. This route of degradation competes with the oxidation pathway previously described. The concentration of 2-MNI in the plasma of pig fed… CONTINUE READING