The hypoxic tumour microenvironment, patient selection and hypoxia-modifying treatments.

@article{Hoogsteen2007TheHT,
  title={The hypoxic tumour microenvironment, patient selection and hypoxia-modifying treatments.},
  author={Ilse J. Hoogsteen and Henri A. M. Marres and Albert J van der Kogel and Johannes Ham Kaanders},
  journal={Clinical oncology (Royal College of Radiologists (Great Britain))},
  year={2007},
  volume={19 6},
  pages={
          385-96
        }
}
Tumour hypoxia has been found to be a characteristic feature in many solid tumours. It has been shown to decrease the therapeutic efficacy of radiation treatment, surgery and some forms of chemotherapy. Successful approaches have been developed to counteract this resistance mechanism, although usually at the cost of increased short- and long-term side-effects. New methods for qualitative and quantitative assessment of tumour oxygenation have made it possible to establish the prognostic… CONTINUE READING

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